U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Tue Oct 22 01:14:10 UTC 2019
Edited
by admin
on Tue Oct 22 01:14:10 UTC 2019
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
DNV5PYD2QS
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
RECEPTOR-TYPE TYROSINE-PROTEIN KINASE FLT3 D835Y
Common Name English
FLT3 D835Y
Common Name English
CD135 D835Y
Common Name English
FLK2 D835Y
Common Name English
FETAL LIVER KINASE-2 D835Y
Common Name English
FLT-3 D835Y
Common Name English
STEM CELL TYROSINE KINASE 1 D835Y
Common Name English
FL CYTOKINE RECEPTOR D835Y
Common Name English
FMS-LIKE TYROSINE KINASE 3 D835Y
Common Name English
Code System Code Type Description
PHAROS
P36888
Created by admin on Tue Oct 22 01:14:10 UTC 2019 , Edited by admin on Tue Oct 22 01:14:10 UTC 2019
PRIMARY
UNIPROT
P36888
Created by admin on Tue Oct 22 01:14:10 UTC 2019 , Edited by admin on Tue Oct 22 01:14:10 UTC 2019
PRIMARY
From To
1_9 1_39
1_77 1_88
1_173 1_180
1_206 1_215
1_246 1_304
1_342 1_381
1_355 1_366
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_17
N 1_74
N 1_125
N 1_280
N 1_297
N 1_325
N 1_328
N 1_447
N 1_476
N 1_515
Related Record Type Details
INHIBITOR -> TARGET
INHIBITOR -> TARGET
CONJUGATED TOXIN->TARGET
LIGAND->TARGET
INHIBITOR -> TARGET
Kd
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
COMPETITIVE INHIBITOR
IC50
INHIBITOR -> TARGET
INHIBITOR -> TARGET
ALSO ACTIVE AGAINST FLT3 ITD and FLT3 D835Y kinases were 1.8 nM and 1.0 nM
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT CHEMICAL