U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Status:
Investigational
Source:
USAN/INN

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
USAN/INN

Class (Stereo):
CHEMICAL (ABSOLUTE)


Status:
Investigational
Source:
USAN/INN

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
USAN/INN

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
USAN/INN

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
USAN/INN

Class (Stereo):
CHEMICAL (RACEMIC)

Status:
Investigational
Source:
USAN/INN

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
USAN/INN

Class (Stereo):
CHEMICAL (RACEMIC)

Status:
Investigational
Source:
USAN/INN

Class (Stereo):
CHEMICAL (ACHIRAL)

Targets:


Description

Streptonigrin is an antibiotic produced by Streptomyces flocculus. Streptonigrin exhibits activity as a broad spectrum antibiotic against both Gram-positive and Gram-negative bacteria. Streptonigrin shows antitumor activity against sarcomas, carcinomas, leukemias and lymphomas in vivo and in vitro. Due to its high toxicity, streptonigrin has not recieved widespread clinical use.
Status:
Investigational
Source:
USAN/INN

Class (Stereo):
CHEMICAL (ABSOLUTE)

CLOTHIXAMIDE MALEATE

MORE DETAILS...
Status:
Investigational
Source:
USAN/INN

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
USAN/INN

Class (Stereo):
CHEMICAL (ABSOLUTE)



Description

Coumermycin is from the aminocoumarin class of antibiotic compounds which acts by inhibiting DNA gyrase. Coumermycin is effective against gram-positive bacteria, but not gram-negative bacteria. Coumermycin its derivatives have been studied since the 1950's as potential antibiotic. However, it has seen little to no clinical development because of its low water solubility, toxicity profile, and ineffectiveness against gram-negative bacteria.
Status:
Investigational
Source:
USAN/INN

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
USAN/INN

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
USAN/INN

Class (Stereo):
CHEMICAL (RACEMIC)